Synapsin W/ Methylcobalamin*** 2 / 50 / 2 mg/mL 15 mL Vial Nasal Spray

Synapsin with Methylcobalamin 2 mg / 50 mg / 2 mg per mL – 15 mL Vial Nasal Spray is a compounded investigational formulation designed to support cognitive function, neuroprotection, and neuronal metabolism. It combines RG3, nicotinamide riboside (NR), and methylcobalamin (active vitamin B12) for synergistic effects on neural and metabolic pathways. RG3 (2 mg/mL) – A bioactive ginsenoside from Panax ginseng, RG3 supports synaptic plasticity, memory, and neuroprotection, while reducing oxidative stress and promoting neuronal survival. Nicotinamide Riboside (50 mg/mL) – NR is a precursor to NAD⁺, essential for mitochondrial function, cellular energy metabolism, and DNA repair, contributing to cognitive resilience and neuroprotective effects. Methylcobalamin (2 mg/mL) – The bioactive form of vitamin B12 supports myelin formation, neurotransmitter synthesis, and nerve regeneration, complementing the neuroprotective properties of RG3 and NR. The 15 mL vial contains a total of 30 mg RG3, 750 mg NR, and 30 mg methylcobalamin, delivered intranasally for rapid absorption through the nasal mucosa, enabling efficient delivery to the central nervous system while bypassing first-pass metabolism. This formulation is intended for research or investigational studies focusing on cognitive enhancement, neuroregeneration, and mitochondrial support. Neuroprotective effects of RG3: https://pubmed.ncbi.nlm.nih.gov/29937252/ Nicotinamide riboside and NAD⁺ metabolism: https://pubmed.ncbi.nlm.nih.gov/29405448/ Methylcobalamin in nerve repair and neuroprotection: https://pubmed.ncbi.nlm.nih.gov/20882480/