Synapsin (RG3 / Nicotinamide Ribose)*** 2 / 50 mg/mL 15 mL Vial Nasal Spray

Synapsin (RG3 / Nicotinamide Riboside) 2 mg / 50 mg per mL – 15 mL Vial Nasal Spray is a compounded investigational formulation designed to support cognitive function, neuroprotection, and cellular energy metabolism. It combines RG3, a ginsenoside derivative, with nicotinamide riboside (NR), a NAD⁺ precursor, to target neural and metabolic pathways. RG3 (2 mg/mL) – A bioactive ginsenoside from Panax ginseng, RG3 has been shown in preclinical studies to enhance synaptic plasticity, memory, and neuroprotection, reduce oxidative stress, and support neuronal survival. Nicotinamide Riboside (50 mg/mL) – NR is a precursor to NAD⁺, a critical coenzyme in mitochondrial function, energy metabolism, and DNA repair. NR supplementation may enhance cellular bioenergetics, support neuroprotection, and improve cognitive resilience. The 15 mL vial contains a total of 30 mg RG3 and 750 mg NR, delivered intranasally for rapid absorption via the nasal mucosa, allowing direct access to the central nervous system while bypassing first-pass metabolism. This route is ideal for research investigating neuroprotective and nootropic effects. Neuroprotective effects of RG3: https://pubmed.ncbi.nlm.nih.gov/29937252/ Nicotinamide riboside and NAD⁺ metabolism in neuroprotection: https://pubmed.ncbi.nlm.nih.gov/29405448/