Rapamycin 5mg capsule

Rapamycin 5 mg Capsule is an oral formulation of sirolimus, a macrolide compound originally derived from Streptomyces hygroscopicus. Rapamycin is an mTOR (mechanistic target of rapamycin) inhibitor, which regulates cell growth, proliferation, protein synthesis, and autophagy. It is FDA-approved for immunosuppressive therapy in organ transplant patients to prevent graft rejection, but it is also studied in research for potential anti-aging, metabolic, and cardioprotective effects. Rapamycin binds to FKBP12, forming a complex that inhibits mTORC1, a critical regulator of nutrient sensing and cellular metabolism. By modulating mTOR signaling, rapamycin can slow cellular senescence, promote autophagy, and influence longevity pathways, which has led to interest in its off-label use in aging research. A 5 mg capsule is a standard clinical dose for transplant immunosuppression, though dosing may differ in investigational or research contexts. Common side effects include immunosuppression, hyperlipidemia, delayed wound healing, and thrombocytopenia, so use must be medically supervised. Clinical pharmacology and immunosuppressive use: https://www.ncbi.nlm.nih.gov/books/NBK470478/ Rapamycin and mTOR inhibition in longevity and metabolic research: https://pubmed.ncbi.nlm.nih.gov/30025591/