Kisspeptin-10 2ml

Kisspeptin-10 2 mL is a synthetic decapeptide derived from the endogenous peptide encoded by the KISS1 gene, playing a central role in regulation of the hypothalamic-pituitary-gonadal (HPG) axis. It acts by binding to the G-protein–coupled receptor GPR54 (also known as KISS1R), stimulating the release of gonadotropin-releasing hormone (GnRH) from the hypothalamus. This, in turn, promotes secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which are essential for reproductive hormone production and fertility regulation. A 2 mL vial typically contains a sterile, liquid or reconstituted solution intended for controlled research or clinical investigation. Kisspeptin-10 is the shortest biologically active fragment of the kisspeptin peptide family and retains full receptor binding affinity, making it widely used in research focused on reproductive endocrinology. Studies have demonstrated that administration of kisspeptin-10 significantly increases circulating LH levels in both men and women, confirming its role as a key upstream regulator of the reproductive hormonal cascade . In addition to reproductive effects, kisspeptin signaling has been implicated in puberty onset, metabolic regulation, and potential therapeutic applications in conditions such as hypogonadotropic hypogonadism. However, due to its short half-life and peptide structure, administration typically requires controlled dosing conditions. Continued research is exploring its broader clinical utility and optimized delivery methods .